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| T-RPMS Home | Editorial Board | T-RPMS in IEEE Xplore | Early Access | Manuscript Submission | ||
| FEATURED STORIES - JULY 2018 | ||
Characterization of X-Ray Acoustic Computed Tomography for Applications in Radiotherapy Dosimetryby Susannah Hickling, Maritza Hobson, and Issam El Naqa X-ray acoustic computed tomography (XACT) is an emerging imaging modality that detects the acoustic waves induced in an object following irradiation by X-ray photons to form an image related to the energy deposited within the object. Since XACT images can be related to deposited radiation dose, it has been proposed that XACT could be an effective dosimetry tool for radiation therapy applications. This paper aims to systematically characterize XACT to determine its capabilities as a radiation dosimetry technique. XACT images of acceptable signal to noise ratio were formed at a dose level as low as 11.6 mGy, and the spatial resolution of XACT was measured to be 6 mm at a linac pulse duration of4 μs. XACT was experimentally shown to be energy and dose rate independent. Changes in field size of 4 mm, field location of 2 mm, and field magnitude of 3% were detectable with XACT. The characteristics of XACT images were observed to be very sensitive to the transducer used for signal detection. Based on these results, XACT has the potential to be a powerful dosimetry tool for radiotherapy dosimetry applications, specifically for relative water tank measurements. more... |
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iMPACT: An Innovative Tracker and Calorimeter for Proton Computed Tomographyby Serena Mattiazzo , Filippo Baruffaldi, Dario Bisello, Benedetto Di Ruzza, Piero Giubilato, Roberto Iuppa, Chiara La Tessa, Devis Pantano, Nicola Pozzobon, Ester Ricci, Walter Snoeys, and Jeffery Wyss This contribution describes the first results obtained within the iMPACT project, which aims to build a novel proton computed-tomography (pCT) scanner for protons of energy up to 230 MeV, as used in hadron therapy. The iMPACT pCT scanner will improve the current state-of-the-art in proton tracking at all levels: speed, spatial resolution, material budget, and cost. We will first describe the design of the iMPACT scanner, which is composed by a tracker and a range calorimeter. We will then illustrate the results of a test with the ALPIDE sensor, a monolithic active pixels sensor, developed by the ALICE collaboration, which will equip the iMPACT tracker in this first phase. We finally detail the characterization building elements of the prototype of the range calorimeter, which is composed of segmented scintillator fingers readout by SiPMs. Reported beam-test data will highlight how the technological choices we made well address the performances of a state-of-the-art pCT system. more... |
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SPECT/MRI INSERT Compatibility: Assessment, Solutions, and Design Guidelinesby Marco Carminati, Giovanni L. Montagnani, Michele Occhipinti, Andre Kuehne, Thoralf Niendorf, Kalman Nagy, Andras Nagy, Miklos Czeller, and Carlo Fiorini In spite of the growing interest in multimodal imaging, and in particular of the consolidation of PET/MRI, the development of simultaneous SPECT/MRI systems is still very limited. SPECT offers potential for multitracer imaging and wider diffusion with respect to PET, but, due to the collimator, poses more stringent challenges on space occupation and MRI compatibility. In this paper, we present a systematic analysis of mutual compatibility between standard 3 T magnetic resonance (MR) scanners and a preclinical SPECT insert composed of a static ring of ten silicon photomultipliers (SiPM)-based gamma cameras. On the MR image quality side, the most critical element is the SPECT tungsten multipinhole collimator, whose distortion of the static field is reduced below 1 ppm thanks to second order shimming. On the SPECT side, MR switching gradients are the most critical source of eddy currents and interferences. Thanks to a board mapping tool, developed for this purpose, the most sensitive tracks and electronic components have been identified and replaced. Shielding, heavy low-pass filtering and star layout of the SiPM high voltage tracks, together with limited use of metallic packages, meshed ground planes, and vias, enabled the preservation of the same energy resolution (14% for99mTc) during MRI. The design guidelines and the experimental results here reported pave the way to MRI compatibility of the clinical version of this insert. more... |
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Scale-Space Anisotropic Total Variation for Limited Angle Tomographyby Yixing Huang, Oliver Taubmann, Xiaolin Huang, Viktor Haase, Guenter Lauritsch, and Andreas Maier This paper addresses streak reduction in limited angle tomography. Although the iterative reweighted total variation (wTV) algorithm reduces small streaks well, it is rather inept at eliminating large ones since total variation (TV) regularization is scale-dependent and may regard these streaks as homogeneous areas. Hence, the main purpose of this paper is to reduce streak artifacts at various scales. We propose the scale-space anisotropic TV (ssaTV) algorithm, which is derived from wTV, in two different implementations. The first implementation (ssaTV-1) utilizes an anisotropic gradient-like operator which uses 2⋅ sneighboring pixels along the streaks’ normal direction at each scales. The second implementation (ssaTV-2) makes use of anisotropic down-sampling and up-sampling operations, similarly oriented along the streaks’ normal direction, to apply TV regularization at various scales. Experiments on numerical and clinical data demonstrate that both ssaTV algorithms reduce streak artifacts more effectively and efficiently than wTV, particularly when using multiple scales. more... |
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A PUBLICATION OF THE IEEE NUCLEAR AND PLASMA SCIENCES SOCIETY |
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| JULY 2018 | VOLUME 2 | NUMBER 4 | ITRPFI | (SSN 2469-7311) | ||
EDITORIAL The Validation Problem of Joint Emission/Transmission Reconstruction From TOF-PET Projections . . J. Nuyts, A. Rezaei, and M. Defrise IMAGE RECONSTRUCTION AND DATA PROCESSING Denoising Low-Dose CT Images Using Multiframe Blind Source Separation and Block Matching Filter . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A. M. Hasan, A. Melli, K. A. Wahid, and P. Babyn Data Consistency for Linograms and Planograms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . R. Clackdoyle Quantitative 4D-PET Reconstruction for Small Animal Using SMEIR-Reconstructed 4D-CBCT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Y. Zhong, F. Kalantari, Y. Zhang, Y. Shao, and J. Wang Scale-Space Anisotropic Total Variation for Limited Angle Tomography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Y. Huang, O. Taubmann, X. Huang, V. Haase, G. Lauritsch, and A. Maier Novel Detection Scheme for X-Ray Small-Angle Scattering . . . . . . . . . G. Li, W. Cong, J. S. Michaelson, H. Liu, L. Gjesteby, and G. Wang Simultaneous Emission-Transmission Tomography in an MRI Hardware Framework . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . L. Gjesteby, W. Cong, Q. Yang, C. Qian, and G. Wang RADIATION THERAPY Characterization of X-Ray Acoustic Computed Tomography for Applications in Radiotherapy Dosimetry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . S. Hickling, M. Hobson, and I. El Naqa iMPACT: An Innovative Tracker and Calorimeter for Proton Computed Tomography . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . S. Mattiazzo, F. Baruffaldi, D. Bisello, B. Di Ruzza, P. Giubilato, R. Iuppa, C. La Tessa, D. Pantano, N. Pozzobon, E. Ricci, W. Snoeys, and J. Wyss PLASMA MEDICINE Plasma-Induced Suppression of Recurrent and Reinoculated Melanoma Tumors in Mice . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . K. Mizuno, Y. Shirakawa, T. Sakamoto, H. Ishizaki, Y. Nishijima, and R. Ono Gradual Deformation of Bacterial Cell Morphology Due to the Effect of Nonthermal Atmospheric Pressure Plasma Jet-Treated Water (PTW) . . . . . . . . . . . . . A. Begum, R. Chiba, T. Ishijima, M. Kakikawa, A. Taoka, M. R. Pervez, T. Innomata, Y. Uesugi, and Y. Tanaka 6TH CONFERENCE ON PET/MR AND SPECT/MR, LISBON, PORTUGAL, MAY 29-31, 2017 SPECT/MRI INSERT Compatibility: Assessment, Solutions, and Design Guidelines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . M. Carminati, G. L. Montagnani, M. Occhipinti, A. Kuehne, T. Niendorf, K. Nagy, A. Nagy, M. Czeller, and C. Fiorini Development of a Practical Calibration Procedure for a Clinical SPECT/MRI System Using a Single INSERT Prototype Detector and Multimini Slit-Slat Collimator . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . D. Salvado, K. Erlandsson, M. Occhipinti, C. Fiorini, J. Willems, P. van Mullekom, Z. Papp, M. Czeller, K. Nagy, and B. F. Hutton |
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